Niedobór testosteronu – czynnik rozwoju chorób układu krążenia u mężczyzn

Autorzy

Wojciech Dobczyński
studenckie koło naukowe przy katedrze i zakładzie biofizyki im. prof. zbigniewa religi, wydział nauk medycznych w katowicach, śląski, uniwersytet medyczny w katowicach
Eliza Barczyk

Streszczenie

Testosteron to główny męski hormon płciowy, najważniejszy przedstawiciel androgenów. Jest on syntetyzowany głównie w jądrach u mężczyzn, a w niewielkich ilościach przez jajniki u kobiet oraz przez nadnercza u obu płci. Występując na poziomach fizjologicznych testosteron wywiera korzystny wpływ na czynności układu sercowo-naczyniowego. Niedobór u mężczyzn prowadzi do zaburzeń metabolicznych i funkcji śródbłonka, dodatkowo niskie stężenie tego hormonu koreluje z występowaniem tzw. zespołu metabolicznego i miażdżycy. Wiąże się to z przedwczesną chorobą wieńcową, niekorzystnym wpływem na czynniki ryzyka chorób układu krążenia i zwiększonym ryzykiem śmiertelności z przyczyn sercowo-naczyniowych niezależnie od wieku. Niskie stężenie tego hormonu jest powiązane ze zwiększoną sztywnością naczyń tętniczych, która predysponuje do wystąpienia arteriosklerozy.

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13 sierpnia 2024