Metody leczenia i perspektywy w terapii atopowego zapalenia skóry
Słowa kluczowe:
AZS, leczenie biologiczne, dermatologia, przeciwciało monoklonalneStreszczenie
Celem pracy był przegląd wybranych innowacji w zakresie leczenia Atopowego zapalenia skóry. Atopowe zapalenia skóry (AZS) jest powszechnym schorzeniem, wpływającym w różnym stopniu na komfort życia pacjentów.Klasyczne metody mają na celu przede wszystkim poprawę komfortu życia pacjenta, poprzez zabiegi zachowawcze takie jak stosowanie emolientów i kąpiele. Nowe metody dotyczące leczenia AZS, skupiają się przede wszystkim na ingerencji w biochemiczne i immunologiczne podstawy patofizjologiczne tej choroby. Wśród nich szczególnie warte uwagi są leczenie biologiczne, substancje wpływające inhibicyjnie na czynniki transkrypcyjne biorące udział w kształtowaniu fazy aktywnej choroby. W ostatnich latach zauważono też niepomijalną rolę mikrobioty skóry, zarówno jako czynnika będącego wypadkowo schorzenia, jak i przyczyną patologii z nią związanych. W pracy wzięto także pod uwagę problematykę leczenia specyficznej grupy jaką są kobiety w ciąży i zastosowania metod o niskim ryzyku wpływu na płód.
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Utwór dostępny jest na licencji Creative Commons Uznanie autorstwa – Użycie niekomercyjne – Bez utworów zależnych 4.0 Międzynarodowe.