Wpływ dysbiozy mikrobioty jelitowej na choroby układu sercowo-naczyniowego

Autorzy

Radosław Szydłowski
Śląski Uniwersytet Medyczny w Katowicach
Patrycja Pabis
Natalia Nafalska
Małgorzata Stopyra

Słowa kluczowe:

choroby sercowo-naczyniowe, mikrobiota jelitowa

Streszczenie

W organizmie człowieka żyje ok. 40 bilionów bakterii. Ich wpływ jest kluczowy na wiele fizjologicznych procesów zachodzących w ciele – trawienie, barierę immunologiczną, regulację układu nerwowego poprzez oś jelito-mózg. Dysbioza mikrobioty jelitowej może powodować upośledzenie wielu z tych reakcji. Udokumentowano zmianę składu mikrobioty jelitowej między innymi w chorobach nerek, układu nerwowego i nowotworach. Poznanie kolejnego organu człowieka, jakim określa się mikrobiotę jelitową, może być kluczowe w prognozowaniu chorób sercowo-naczyniowych. Obecnie przeprowadzane są badania na zwierzętach, których wyniki są obiecujące i stanowią podstawę do dalszych rozważań. Celem niniejszej pracy jest przedstawienie powiązania zaburzenia składu mikrobioty jelitowej z chorobami układu sercowo-naczyniowego.

Rozdziały

  • Wstęp
  • Skład mikrobioty jelitowej u człowieka
  • Funkcje mikrobioty jelitowej
  • Migotanie przedsionków
  • Mikrobiota jelitowa a nadciśnienie tętnicze
  • Mikrobiota jelitowa a zawał serca
  • Mikrobiota jelitowa a udar mózgu
  • Zmiana mikrobioty jelitowej
  • Wnioski i podsumowanie

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