Innowacje w powłokach implantów medycznych kluczem do prawej oteointegracji
Słowa kluczowe:
implant, powłoka, ortopedia, osteointegracjaStreszczenie
Wraz ze starzeniem się społeczeństwa rośnie liczba wykonywanych zabiegów alloplastyki. Część pacjentów będzie wymagała rewizji endoplastyki z powodu komplikacji, jak zakażenia czy obluzowania. Rozwiązaniem może być zastosowanie nowoczesnych technologii w tworzeniu funkcyjnych powłok na powierzchni implantu. Powłoka implantu pełni kilka funkcji. Z jednej strony zwiększa wytrzymałość implantu oraz zapewnia jego bezawaryjność, z drugiej umożliwia prawidłowy przebieg procesu osteointegracji. Najnowsze badania nad powłokami stawiają nacisk na właściwości antyseptyczne powłoki oraz zapewnienie dobrej powierzchni przylegania do kości co zapewnia przyspieszenie procesu osteointegracji. Efekty te są możliwe dzięki zastosowaniu: nanopowłok, jonów metali zaimplementowanych w powłoki, czynników biologicznych i immunologicznych modulujących działanie komórek organizmu oraz materiałów biologicznie czynnych. Uwagę badaczy skupiają również powłoki kombinowane, prezentujące wieloczynnikowe, inteligentne działanie zdolne do uwalniania czynników przy odpowiednich warunkach po wszczepieniu w ciało. W pracy skupiono się na przedstawieniu najważniejszych metod ich sporządzania, procesu integracji implantu z kością tj. osteointegracji, oraz przedstawienia najnowszych zdobyczy inżynierii biomateriałowej w tej dziedzinie.
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Opublikowane
13 czerwca 2023
Prawa autorskie (c) 2023 Rafał Kołodziej; Patrycja Piłat, Małgorzata Dyga, Zuzanna Kasieczka
Licencja
Utwór dostępny jest na licencji Creative Commons Uznanie autorstwa – Użycie niekomercyjne – Bez utworów zależnych 4.0 Międzynarodowe.
